Antonio E. Lewis is a go-to trial lawyer for Fortune 500 corporations and major companies defending high-stakes product liability, pharmaceutical, toxic tort, and environmental litigation in state and federal courts across the country. With more than twenty years of courtroom experience and more than a dozen jury trials as first or second chair — including multiple recent trial victories in pharmaceutical product liability litigation and favorable outcomes in tobacco, pharma, and consumer products disputes — and additional courtroom experience across scores of other matters, he brings a volume and depth of first-chair trial experience that is increasingly rare in the defense bar.
Antonio represents leading pharmaceutical manufacturers, consumer products companies, industrial clients, and major automotive and technology companies in product liability, mass tort, toxic tort, and complex commercial matters spanning the pharmaceutical, consumer products, chemical, automotive, and energy industries. His practice covers established mass tort dockets and bet-the-company disputes in some of the nation's most demanding jurisdictions. He also brings a distinctive foundation of intellectual property trial experience — having handled patent, copyright, trademark, and trade secret disputes alongside professional liability and class action matters — a combination that sharpens his ability to manage document-intensive, technically complex cases at trial. Antonio previously served as chief litigation counsel for a Fortune 500 advanced-technology company, where he managed a global portfolio of disputes spanning commercial, product liability, intellectual property, compliance, insurance coverage, and government investigations — experience that gives him a practical understanding of the business pressures and strategic priorities his clients face.
Antonio joined King & Spalding to try big cases and has done exactly that, building his trial record from the courtroom up. He is equally effective before judges and juries — delivering opening statements, cross-examining fact and expert witnesses, presenting closing arguments, and arguing complex pre-trial and dispositive motions. He is known for meticulous preparation, the ability to synthesize complex scientific and technical evidence for lay audiences, and a relentless commitment to mastering every detail of the record. His colleagues describe him as someone whose courtroom judgment and steadiness under pressure set the standard for the next generation of defense trial lawyers.
